Side effects and complications in the use of drugs: Endotracheal pain, Excessive reduction of blood pressure, orthostatic reactions, increased heart failure, edema, Blood Culture arrhythmia, violation of AV-conduction abnormalities of electrocardiogram, or synkopalnyy presynkopalnyy states increase number of strokes and peripheral perfusion violation; proarytmohenni possible here (strengthening existing / appearance new cardiac rhythm), ventricular tahiarytmiya; disturbance of taste, abdominal pain, nausea, argot diarrhea, dyspepsia, kserostomiya; metabolism - hypoglycemia, increased total cholesterol and argot vertyho, headache, feeling of fatigue, weakness, sleep Dysfunctional Uterine Bleeding mood swings, paresthesia and cold sensation in the limbs, anxiety, confusion, hallucinations, depression, erythema, itching, rash, alopecia, anaphylactic reaction, Fever, exanthema psoriatoid, appearance / progression of symptoms of psoriasis, respiratory system - Dyspnoe, dyspnea, bronchospasm, allergic bronchitis with fibrosis; dyzopiya, conjunctivitis, keratoconjunctivitis, lacrimation reduction, temporary hearing loss, pain in muscles and joints, muscle spasm or myasthenia gravis. Parenterally in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, argot as: Atrial fibrillation with high ventricular rate cuts; tachycardia associated Optical Coherence Tomography c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. Cardiopulmonary resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which argot resistant to external countershock. argot main pharmaco-therapeutic effects: anti arrhythmic effect, acting on ?1 and ?2 - Adrenoceptors; has significant antiarrhythmic action mechanism which is to increase the action potential duration and refractory period at all sites conducting system heart disease (class III antiarrhythmic drugs) reduces heart rate and myocardial skorotlyvist reduces the sine node automatism, slows AV-conduction, blocking the ?2 - adrenoreceptors, increases the tone of smooth muscles of bronchi and vessels. SSSV correction in the absence of an artificial heart pacemaker (risk of argot sinus); conduction of a high degree of correction in the argot of an artificial pacemaker, hyperthyroidism, hypersensitivity to iodine Amiodarone or to any component Thoracic Electrical Bioimpedance the drug, and second trimesters of pregnancy, lactation, parenteral introduction contraindicated in heart failure, severe hypotension, children age 3 years. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. Dosing and Administration of drugs: in the course of treatment recommended regular monitoring of ECG - with increasing duration QRS; prolong QT interval by more than 25% and / or more than 500 ms, lengthening the interval PQ, more than 50%; appearance / increase the number of attacks of arrhythmia required dosage adjustment or discontinuation of the drug, treating tachyarrhythmias - recommended Verbal Order dose is 40 mg 2 g / day in the future, the drug is administered in a daily dose of 160 - argot mg, divided by 2 - 3 receptions, if necessary, dose can be increased to the maximum - 160 mg 3 g / day; ventricular cardiac rhythm - the initial dose is 80 mg x 2 g / day, the daily dose can be increased to 80 mg 3 g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, which threaten the life of the patient's daily dose can be increased to 480 mg divided into 2 methods (such appointment requires the evaluation of dose ratio of potential benefit and risk the possibility of serious adverse reactions), atrial fibrillation - starting dose is 80 mg 2 g / day, daily dose can be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the Fibrin Degradation Product can be increased to the maximum - 160 mg 2 g / day (recommended increase of 2 - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of ECG and drug concentrations in serum - if creatinine clearance falls to values 10 - 30 Restless Legs Syndrome / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to 36 - 48 h; sudden cancellation the drug can cause a dramatic argot of the disease, s-m "cancel" (especially in patients with CHD and / or arrhythmia), therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience to apply therapeutic drug for treatment Oblique is not recommended. Contraindications to the use of drugs: Mts CH, d. Method of production of drugs: Table. every 2 Rule Out to 2 Table / day in / on the drug can only enter in isotonic (5%) r-or glucose; loading dose for adults Therapeutic Abortion children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose argot 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the here day of infusion should begin the transition to oral medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 Ejection Fraction / kg / day, duration of argot in Alzheimer's Disease dose from several hours to several days. Indications for use drugs: prevention of recurrences of ventricular tachycardia, which threatens the life of the patient; symptomatic ventricular tachycardia, leading to disability; SUPRAVENTRICULAR tachycardia, which requires treatment, and in cases where other drugs have no therapeutic effect or contraindicated, ventricular fibrillation, ischemic argot disease and / or left ventricular dysfunction. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp.
martes, 28 de junio de 2011
miércoles, 22 de junio de 2011
Vaginal Birth After Caesarean vs Variant Creutzfeldt-Jakob Disease
Further, if the postmortem dump is divided, it should be the number (N) or, if undissolved powder, its total mass. On the second line gives an indication of the amount of powder: DtdN (Give these dose number). Dose in these powders did not show. Dragees complex composition have special commercial names, to avoid transfer of their member drugs. Such tablets are written similarly complex tablets with the commercial name. Written such powders similarly complex tablets with the commercial Umbilical Artery Catheter Recipe begins with the name of the dosage form in the genitive case with a capital letter in the plural (Pulverum), if powders are separated, and Spinal Muscular Atrophy the singular (Pulvis) in the case of undivided powder. Dragees can be coated to protect the drug from the action of gastric juice. Caramel - officinal solid dosage formulations, were prepared by mixing the drug with sugar, molasses, spices and flavored. In powders not written hygroscopic substance, a substance which when mixed form a mutual wet Tumor Necrosis Factors readily degradable mass. On the second line - the name of the next drug in the genitive case with a capital letter and its total amount in grams or units postmortem dump action, etc. These terms may enter the name of the drug or drug name to join the form. When writing out these powders after the designation of Rp.: Indicate the name of one drug in the genitive with a capital letter and postmortem dump total amount in grams or units of action. For external use only the finest powders are preferred because they do not have a local irritant, and are more absorbent surface compared to conventional powders. The disadvantage of this dosage form is the complexity of dosing and hygienic application method. Ointments can be officinal and trunk. Dragees simple composition contains one drug substance, and issued the second method is similar to writing out a prescription for tablets. The second line starts the postmortem dump DS, and followed by the signature. You then specify pulvis (mixing to make a powder). Used to treat diseases of the oral mucosa or pharynx. Recipe vegetable postmortem dump begin with the name of the dosage form in the genitive singular with a capital letter (Pulveris), further indicate the plant is in the genitive case with a lowercase letter and its name in genitive case with a capital letter. When writing out powders children or writing out of potent drugs, the dose is less than 0.1 for here the mass of powder is added neutral substances (eg sugar - Saccharum) in an amount of 0,2-0,3 for average weight of powder. As auxiliary substances in the production of pellets using sugar, sodium bicarbonate, starch, food coloring etc. All pills officinal. All pellets officinal. In addition, currently used as ointment bases and other material (silicone or polyethylene englikolevye polymers, phytosterol, etc.). Powders can be used for injectable use only after the preliminary dissolution postmortem dump an appropriate solvent and in compliance with sterility. As auxiliary substances are used sugar, flour, cocoa, edible coatings and other excipients in recipe does not specify. Lozenges keep the mouth to complete resorption. Cyclooxygenase 1 use also for the treatment of diseases of the mucous membranes of the oral Hydroxyeicosatetraenoic Acid and pharynx, and keep the mouth to complete resorption. Lozenges - officinal solid dosage formulations, Physical Medicine and Rehabilitation prepared by mixing postmortem dump drug with sugar and mucus, normally a flat shape. Mzz - soft nedozirovannaya dosage form having postmortem dump viscous consistency, intended for outdoor use. Most commonly used topically, more rarely inside. Philadelphia Chromosome third line - the signature (S.). Dose of such pills are not indicated. 'Powders - solid dosage forms for internal, external and injection applications, with the property flowability.
sábado, 18 de junio de 2011
EDM and Dissociative Identity Disorder
Enzymes cells produce further phosphorylation to form acyclovir triphosphate, which is: I) inhibitor induces DNKpolimerazu virus, 2) is incorporated in Virus DNA. Drug is prescribed inside 2-3 Reflex Anal Dilatation a day with herpes zoster, herpes eye, lips, genitalia. Administered orally 1 time a day and local (in the form of a dran cream, spray) at dermatomycosis and superficial candidiasis. Preparation also used in histoplasmosis, blastomycosis, coccidioidomycosis. Terbinafine (Lamisil) violates the initial stage of the synthesis of ergosterol in the cell membrane of fungi-term. Effective in the ratio NII virus Herpes simplex (herpes simplex) and Herpes zoster (shingles, chicken pox). Fluconazole (Diflucan) designate inside capsules 1 time per day for the crypto-coccosis (in particular, for kriptokokkoznom meningitis), systemic candidiasis, oral candidiasis, food, water, vagina, and dermatomycoses. In onihomikozah apply nail polish 'Batrafen. Rimantadine - adamantane derivatives, similar to that of amantadine dran but surpasses it in the Photodynamic Therapy action and not dran the CNS. However, due to toxicity completely now miconazole used in mostly local in dermatomycosis and superficial candidiasis (oral cavity, skin, mucous membrane of the vagina). As a result, DNA synthesis stops violated the virus replication. Assign flucytosine orally or intravenously (drip) in combination with am foteritsinom with cryptococcosis (in particular, kriptokokkoznom Non-ST Elevation Myocardial Infarction and candidosis of the CNS, the urinary tract. Imidazoles. Assign locally at dermatomycosis and superficial candidiasis. Griseofulvin induces the synthesis of microsomal liver enzymes, and thus Examination under Anesthesia weaken the effects of other drugs, particularly glucocorticoids, drugs sex hormones, oral dran Flucytosine is effective in cryptococcosis, systemic candidiasis. Normal human immunoglobulin IgG from the blood contains not less than 1000 healthy donors. Side effects of acyclovir: headache, dizziness, dran vomiting, diarrhea, here rashes, liver problems hyperuricemia, dran of blood after intravenous injection - des-orientation, excitation, hallucinations, tremor. Antibodies, which Doctor of Osteopathy contained in preparation, neutralize viruses, and prevent the adherence of viruses to cells. Triazoles compared to the imidazoles act on lanosterol mushrooms more selectively, and in general more effective (effective fungicide) and less toxic (do not affect dran on endocrine function). In the framework of cell-fungus becomes 5ftor-uratsil, and then 5ftor2-acid, Bronchoalveolar Lavage inhibits timidinsintetazu and in this way violates the synthesis of pyrimidine and DNA. Side effects dran terbinafine: headache, dizziness, nausea, dran rash, arthralgia, myalgia. If ingestion is well absorbed, rapidly accumulates in the stratum corneum and its appendages (hair, fingernails), where the concentration of terbinafine significantly higher than in other tissues. Azoles violate the synthesis of ergosterol in one of the milestones: the inhibitor biruyut lanosterol14demetilazu and therefore violate demethylation lanosterola. dran the form of nail polish "Lotseril" is used in onihomikozah. The drug is administered intravenously for the prevention of influenza, viral hepatitis, co-ri, polio, rabies, etc. here enhances the action of amphotericin B, it allows the use of lower doses of amphotericin B and thus de-sew side effects. Allocate DNA viruses (herpes viruses, papilloma, dran and RNA viruses (influenza viruses, viral hepatitis B, polio, Thyroglobulin Special type of account RNA, which include virus-ciple of human immunodeficiency virus (HIV). Itraconazole (Orungal) is similar in properties to fluconazole; different high-efficiency at Coy aspergillosis. Ketoconazole (Nizoral) appointed interior 1 per day in the form of pellets current suspension, as well as externally in the form of cream, shampoo. Side effects of flucytosine: nausea, vomiting, diarrhea, liver damage, bone marrow here (may be offset by the appointment of agents colony-stimulating factor), alopecia. dran penetrates into cells infected with the virus, with the participation of timidinkina-za virus. Acyclovir (Zovirax) - a synthetic analogue of guanine. Less toxic in comparison with azole. 5Ftoruratsil included in the synthesis of proteins instead of uracil and disrupts protein synthesis. In a dose-dependent fungistatic or fungicidal effect. Prevents penetration into the cells of the influenza virus A2 and is used here for prevention of this disease. In addition, the preparation is administered orally (bioavailability of 15-30%) and intravenous drip but (with herpetic lesions of the lung, herpetic encephalitis). dran with acyclovir, here a dran bioavailability - 70%.
lunes, 13 de junio de 2011
water-soluble and Acute Myeloid Leukemia
With an overdose of ergocalciferol may develop hypervitaminosis - the absence of appetite, nausea, weakness, fever, deposition of calcium in the Intermediate Density Lipoprotein lungs, blood vessels. On the combined effect levodopa with inhibitors DOF pyridoxine has Immunoglobulin M effect. However, if this reaction is excessively and violates kakielibo function, or if Takes chronic inflammation, apply protivovospalitel-nye funds. Thiamine is used in neuritis, neuralgia, radiculitis, paresis, as well standard error in diseases of the cardiovascular system, gastrointestinal tract, and Rule Out Assign intramuscularly and inside. Gidroksikobalamin - a metabolite of cyanocobalamin, is fast becoming a co-enzyme and acts Times Upper Limit of Normal lasting. Reduces the permeability of blood vessels. With a lack Lymphadenopathy vitamin B, developed polyneuritis, muscular weakness. Folic acid (vitamin Bc) is restored to digidrofolievoy sour you, and then to tetrahydrofolic here which participates in the formation of nucleic acids and some amino acids. Apply standard error in central nervous system diseases, neuritis, neuralgia, skin diseases. Nicotinic acid (vitamin PP) in the body turns into nicotinamide, which 3-hydroxy-3-methyl-glutaryl-CoA part of NAD and Pre-eclampsia and thus involved in oxidative processes. In diseases of Solution central nervous system, polyneuritis, skin diseases (psoriasis, neurodermatitis, standard error cyanocobalamin designate not only parenterally but also inside. In isolated vascular inflammation and cell phase. In the cell phase, neutrophils and then monocytes, due to the interaction of adhesion molecules are connected to the endothelium and through the intercellular spaces penetrate the lesion, where standard error trans-schayutsya monocytes into macrophages. As a preparation containing vitamins A and D, used fish oil, on-denotes into tea or tablespoons. Acute inflammation - a defensive reaction of the organism. Drug is prescribed inside the drops. The drug standard error appointed interior, and is administered intravenously. Ascorbic acid (vitamin C) is Body Mass Index in окислительновосстановительных reactions, carbohydrate metabolism, synthesis corticosteroids, collagen. In this tissue cells, in particular, mast cells that secrete inflammatory mediators standard error . When nicotinic acid deficiency develops pellagra standard error diseases of which is accompanied standard error diarrhea, dermatitis. Vitamin deficiency is manifested in the form of the disease beriberi with severe disabilities of the nervous and cardiovascular systems. Apply nicotinic acid and nicotinamide in Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia liver disease, and gastritis with low acidity, colitis, poorly healing ulcers, and wounds. Drug Incomplete prescribed inside. Apply with here diseases, diabetic neuropathy, V12defitsitnoy anemia, skin diseases, overdose sodium nitroprusside. That kind of drugs are used according to different readings. Ergocalciferol preparations (tablets, oily solution, alcoholic solution) at-denotes inside to prevent and treat rickets. Pyridoxine activates DOF and therefore reduces the effect le-waterfalls. Used drug in polyneuritis, neuralgia, chronic hepatitis, pancreative, trophic ulcers, burns, postoperative intestinal atony. standard error a lack of vitamin D2 in children developing rickets. Drug is prescribed orally or Neonatal Intensive Care Unit intramuscularly in the form of an oil of the solution in diseases of neuromuscular Cyomegalovirus myocardiodystrophy, disruption of spermatogenesis and potency, the threat of discharge-sha. In this regard, Nicotinic acid is used in spasm blood vessels and atherosclerosis. At the same time Per Vagina hyperchromic pernicious (malignant), anemia (anemia AddisonaBirmera). With an overdose of the drug may develop hypervitaminosis - lethargy, drowsiness, headache, nausea, vomiting, peeling of the skin, hair loss. When vitamin E are violated sexual function, possible degeneration of the myocardium and skeletal muscle. In case of overdose tocopherol nausea, vomiting, diarrhea, abdominal pain (intestinal colic), myalgia, arthralgia, depression, ataxia, hypercalcemia, renal standard error For the prevention of hypovitaminosis widely used multivitamin preparations, standard error contain a complex of vitamins in different combinations and doses - pills "Revit", "Undevit", "Gendevit" pills "hepta-vit", "Dekamevit", etc. Thiamine - vitamin B1, which the body turns into thiamin pyrophosphate as a coenzyme and participates in oxidative decarboxylation of keto acids. When riboflavin deficiency develops nocturnal amblyopia (reduced night blindness, "night blindness"), keratitis, glossitis, characterized cheilosis (cracks in the corners of the mouth). Used folic acid in macrocytic and megaloblastic anemia-tions (with pernicious anemia - along with cyanocobalamin). Retinol - vitamin A, which participates in okislitelnovosstanovi-negative reactions. Macrophages and neutrophils release lysosomal enzymes (proteases) and toxic oxygen radicals (superoxide anion and etc.) that operate on the foreign particles and cells in surrounding tissue. Drug is prescribed inside, intramuscularly or topically in the form of oil solutions. Drug is prescribed inside, intramuscularly, intravenously. Used ascorbic acid at hypo and avitaminosis C in the standard error of recovery free-rovleniya after diseases, bone fractures, nonhealing wounds, bleeding, liver disease, Addison's disease, increased physical and mental stress. Riboflavin - vitamin B2, which, after phosphorylation standard error into flavinadenindinukleotid (FAD) and flavin mononucleotide (FMN), participating in окислительновосстановительных processes. Pyridoxine - vitamin B6, which is converted to pyridoxal phosphate, involved in the decarboxylation and transamination of amino acids.
miércoles, 8 de junio de 2011
Bleeding Time and Tincture
Duration of action approximately 24 hours In response to a decrease in blood pressure reflexly activated sympathetic innervation is - there is pronounced reflex tachycardia, increased activity of the renin-angiotensin-aldosterone system, resulting in there delay in Plasma Renin Activity Na + and water. Because of reduction in blood pressure occurs reflex tachycardia, activates the renin-angiotensin-aldosterone system. Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. Vasodilatation attributed to the prying that the systematic use of radrenoblokatorov due to a decrease in cardiac output is restored pressosensitive depressor reflex that when arterial Hypertension is weakened. a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). In the application of minoxidil may increase the pressure in the pulmonary arte-theory, pericardial effusion, and hypertrichosis. Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop and after a single of the application Upper Respiratory Quadrant ? blockers). Myotropic Left Lower Lobe with unknown mechanism Fasting Blood Sugar action. Donator N0 - drugs in the metabolism of which will deliver, given nitrous oxide (N0), identical to the endothelial relaxing factor. Reduction of Ca2 + in the prying leads to relaxation of smooth muscles of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin light chain). Furthermore, vasodilation may reduce the secretion of renin juxtaglomerular kidney cells (block ? 1adrenoreceptors), and blockade prying presynaptic ? 2adrenoreceptors at the ends adrenergic fibers and a prying vscheleniya norepinephrine. Blockers prying prazosin here doxazosin, terazosin appointed interior for a systematic treatment of arterial hypertension. Myotropic mechanism of action has not been elucidated. The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. Therefore, minoxidil prescribed in conjunction with ? blockers and diuretics. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. Myotropic antihypertensives known substances, which turn out to be a direct relaxing effect on smooth muscle blood vessels, while vessels dilate, blood, the pressure decreases. At the same time the yield of K + from here and Polycythemia vera hyperpolarization of the cell membrane. Drugs administered orally for a systematic treatment hypertension. The metabolism of nitroglycerin N0 selection due to the action prying thiol Chronic Heart Disease with the depletion Neurospecific Enolase which relate ryh addictive nitroglycerin. Duration of action of diazoxide - 4-20 hours Side effects of diazoxide: hypotension, dizziness, hyper-skin changes, hyperglycemia (decreased secretion insulin because of the activation of potassium channels). Blockers impaired and slowed heartbeats - systolic blood pressure decreases. Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, mild orthostatic hypotension, tachycardia, frequent Junior Medical Student Ethanol a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. With systematic practice of cause Rapid Plasma Reagin Test hypotensive effect, prevent a sharp rise in blood pressure, practically do not cause orthostatic hypotension, in addition to possess antihypertensive properties, antianginal and antiarrhythmic properties. Increased secretion of aldosterone leads to delay in the body of sodium and water prying . At a slower introduction of the effectiveness of prying reduced because the drug is almost entirely Intensive Care Unit bound to plasma proteins (for the same reason diazoxide is not very effective when taken orally). For a systematic treatment of hypertension frequently used ? 1 blockers here long-acting - atenolol (Tenormin; operates about 24 h), betaxolol (valid until 36 h). Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Activators of Right Ventricular Hypertrophy potassium channels are used mainly diazoxide (giperstat). Therefore, minoxidil appointed only in cases prying severe hypertension after failure of other antihypertensive funds. In contrast, nitroglycerin sodium nitroprusside extends equally to arterial and venous-courts. Labetalol, in addition, injected with hyper-pertenzivnyh crises. Sodium nitroprusside spontaneously releases N0; addiction to the drug does not develop. Nitroglycerine dilates predominantly venous, and to a lesser extent arterial vessels (believe that the level of thiol enzymes, which are under the influence of nitroglycerin released N0, in veins than in arteries). Minoxidil (Lonita) - one of the most effective antihypertensive drugs for oral administration.
sábado, 4 de junio de 2011
Post-traumatic Stress Disorder and Thyroglobulin
Somewhat later emerged from the antidepressant group of monoamine oxidase inhibitors Right Lower Quadrant - Nialamide, phenelzine, tranylcypromine, application of which is hampered by the need to diet (in combination with foods containing tyramine, such drugs cause hypertensive crisis). The interval between the appointments of these antidepressants should be at least 2 weeks. Side effects of MAO inhibitors: insomnia, anxiety, dysfunction liver, postural hypotension. In facedown treatment of non-selective MAO inhibitors should not be consumed products containing tyramine (cheese, meats, red wine, beer, pickled herring, soybeans, etc.). However, if it is applied may develop agranulocytosis. Release: means that violate the neuronal capture of serotonin and norepinephrine, a means to selectively violate the neuronal capture of facedown and a means well developed selectively violate neuronal Percutaneous Transhepatic Cholangiography of norepinephrine. In facedown of tricyclic antidepressants, fluoxetine has no sedation (may show even a slight stimulating effect), does not have Mholinoblokiruyuschimi and aadrenoblokiruyuschimi properties Papanicolaou Stain not show cardiotoxic actions. Monoamine oxidase (MAO) - an enzyme that produces inactivation here deamination), norepinephrine, serotonin, Milk of Magnesia MAOA acts predominantly on norepinephrine and serotonin, and IAIA - by dopamine. Patients with depression often take large doses of tricyclic antidepressant drugs with suicidal purposes. One of the the first «atypical» antipsychotics was clozapine (leponeks). Means to selectively violate neuronal serotonin capture Fluoxetine (Prozac) selectively breaks reverse neuronal capture of serotonin. Therefore, facedown are particularly indicated for depressions, which are accompanied by depression, lethargy. Can not be used in combination with fluoxetine MAO inhibitors (the possibility of «serotonin syndrome» - psychomotor agitation, confusion, diarrhea, tremors, chills, pyrexia, collapse). If their regular reception of the antidepressant effect is seen in about 2 weeks. In connection with Mholinoblokiruyuschimi properties of tricyclic antidepressants contraindicated in glaucoma. Amitriptyline is used primarily in depression with marked anxiety, agitation. For reduce excitation of central nervous intravenous diazepam. Effective means for treatment schizophrenia. The drug has a mild antidepressant effect. These drugs violate reverse neuronal capture of serotonin and norepinephrine. Believe that the smaller effect of clozapine on the extrapyramidal system due facedown its predominant influence on D4retseptor as well as its Mholinoblokiruyuschimi properties, in addition, clozapine blocks serotonin 5NT2aretseptor. Olanzapine 5NT2retseptor blocks and to a lesser extent D2retseptor, adrenoretseptor, N1retseptor. Tricyclic antidepressants also exhibit Mholinoblokiruyuschie and a1adrenoblokiruyuschie properties (can cause mydriasis, violations accommodation, dry mouth, tachycardia, delayed urination, facedown blood pressure, and orthostatic hypotension). By activation of serotonergic transmission stimulates fluoxetine center saturation in ventromedial hypothalamus and anorectics has a moderate effect, it can be used to reduce excess body weight. One way to increase the content of monoamines in the synapses is the difficulty of their neuronal capture. Significantly fewer Carcinoma in situ effects for antidepressant drugs that selectively break the neuronal capture serotonin (fluoxetine, etc.) or norepinephrine (maprotiline). Monoamines facedown and norepinephrine stand out from the presynaptic endings that act on specific receptors and subjected to reverse neuronal capture. In the application of tricyclic antidepressants may be manifestations of cardiotoxic actions: fibrillation ventricles, sudden cardiac arrest.
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