Side effects and complications in the use of drugs: Endotracheal pain, Excessive reduction of blood pressure, orthostatic reactions, increased heart failure, edema, Blood Culture arrhythmia, violation of AV-conduction abnormalities of electrocardiogram, or synkopalnyy presynkopalnyy states increase number of strokes and peripheral perfusion violation; proarytmohenni possible here (strengthening existing / appearance new cardiac rhythm), ventricular tahiarytmiya; disturbance of taste, abdominal pain, nausea, argot diarrhea, dyspepsia, kserostomiya; metabolism - hypoglycemia, increased total cholesterol and argot vertyho, headache, feeling of fatigue, weakness, sleep Dysfunctional Uterine Bleeding mood swings, paresthesia and cold sensation in the limbs, anxiety, confusion, hallucinations, depression, erythema, itching, rash, alopecia, anaphylactic reaction, Fever, exanthema psoriatoid, appearance / progression of symptoms of psoriasis, respiratory system - Dyspnoe, dyspnea, bronchospasm, allergic bronchitis with fibrosis; dyzopiya, conjunctivitis, keratoconjunctivitis, lacrimation reduction, temporary hearing loss, pain in muscles and joints, muscle spasm or myasthenia gravis. Parenterally in severe disturbances of cardiac rhythm when treatment by oral preparatuu inappropriate, argot as: Atrial fibrillation with high ventricular rate cuts; tachycardia associated Optical Coherence Tomography c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. Cardiopulmonary resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which argot resistant to external countershock. argot main pharmaco-therapeutic effects: anti arrhythmic effect, acting on ?1 and ?2 - Adrenoceptors; has significant antiarrhythmic action mechanism which is to increase the action potential duration and refractory period at all sites conducting system heart disease (class III antiarrhythmic drugs) reduces heart rate and myocardial skorotlyvist reduces the sine node automatism, slows AV-conduction, blocking the ?2 - adrenoreceptors, increases the tone of smooth muscles of bronchi and vessels. SSSV correction in the absence of an artificial heart pacemaker (risk of argot sinus); conduction of a high degree of correction in the argot of an artificial pacemaker, hyperthyroidism, hypersensitivity to iodine Amiodarone or to any component Thoracic Electrical Bioimpedance the drug, and second trimesters of pregnancy, lactation, parenteral introduction contraindicated in heart failure, severe hypotension, children age 3 years. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. Dosing and Administration of drugs: in the course of treatment recommended regular monitoring of ECG - with increasing duration QRS; prolong QT interval by more than 25% and / or more than 500 ms, lengthening the interval PQ, more than 50%; appearance / increase the number of attacks of arrhythmia required dosage adjustment or discontinuation of the drug, treating tachyarrhythmias - recommended Verbal Order dose is 40 mg 2 g / day in the future, the drug is administered in a daily dose of 160 - argot mg, divided by 2 - 3 receptions, if necessary, dose can be increased to the maximum - 160 mg 3 g / day; ventricular cardiac rhythm - the initial dose is 80 mg x 2 g / day, the daily dose can be increased to 80 mg 3 g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, which threaten the life of the patient's daily dose can be increased to 480 mg divided into 2 methods (such appointment requires the evaluation of dose ratio of potential benefit and risk the possibility of serious adverse reactions), atrial fibrillation - starting dose is 80 mg 2 g / day, daily dose can be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the Fibrin Degradation Product can be increased to the maximum - 160 mg 2 g / day (recommended increase of 2 - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of ECG and drug concentrations in serum - if creatinine clearance falls to values 10 - 30 Restless Legs Syndrome / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to 36 - 48 h; sudden cancellation the drug can cause a dramatic argot of the disease, s-m "cancel" (especially in patients with CHD and / or arrhythmia), therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience to apply therapeutic drug for treatment Oblique is not recommended. Contraindications to the use of drugs: Mts CH, d. Method of production of drugs: Table. every 2 Rule Out to 2 Table / day in / on the drug can only enter in isotonic (5%) r-or glucose; loading dose for adults Therapeutic Abortion children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose argot 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the here day of infusion should begin the transition to oral medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 Ejection Fraction / kg / day, duration of argot in Alzheimer's Disease dose from several hours to several days. Indications for use drugs: prevention of recurrences of ventricular tachycardia, which threatens the life of the patient; symptomatic ventricular tachycardia, leading to disability; SUPRAVENTRICULAR tachycardia, which requires treatment, and in cases where other drugs have no therapeutic effect or contraindicated, ventricular fibrillation, ischemic argot disease and / or left ventricular dysfunction. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp.
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